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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737195
Species: Homo sapiens
RGD Object: Gene
Symbol: JUNB
Name: JunB proto-oncogene, AP-1 transcription factor subunit
Acc ID: CHEBI:4469
Term: (S)-amphetamine
Definition: A 1-phenylpropan-2-amine that has S configuration.
Chemical ID: MESH:D003913
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
JUNBincreases expressionISOJunb (Rattus norvegicus)6480464CTDDextroamphetamine results in increased expression of JUNB mRNAPMID:1347779
JUNBincreases expressionISOJunb (Mus musculus)6480464CTDDextroamphetamine results in increased expression of JUNB mRNAPMID:12205029
JUNBmultiple interactionsISOJunb (Rattus norvegicus)6480464CTDReserpine promotes the reaction [Dextroamphetamine results in increased expression of JUNB mRNA]; SCH 23390 inhibits the reaction [Dextroamphetamine results in increased expression of JUNB mRNA]; SCH 23390 inhibits the reaction [Reserpine promotes the reaction [Dextroamphetamine results in increased expression of JUNB mRNA]]PMID:1347779
JUNBmultiple interactionsISOJunb (Mus musculus)6480464CTDSOD1 inhibits the reaction [Dextroamphetamine results in increased expression of JUNB mRNA]PMID:12205029
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