GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Agtr1a | multiple interactions | EXP | | 6480464 | CTD | [Perindopril co-treated with AM6545] inhibits the reaction [Streptozocin results in increased expression of AGTR1A protein]; Perindopril inhibits the reaction [Streptozocin results in increased expression of AGTR1A mRNA]; Perindopril inhibits the reaction [Streptozocin results in increased expression of AGTR1A protein] | PMID:30184259 | Agtr1a | affects response to substance | ISO | AGTR1 (Homo sapiens) | 6480464 | CTD | AGTR1 gene SNP affects the susceptibility to Perindopril | PMID:8952600 | Agtr1a | multiple interactions | ISO | Agtr1a (Rattus norvegicus) | 6480464 | CTD | Perindopril inhibits the reaction [Carbon Tetrachloride results in increased expression of AGTR1A mRNA]; Perindopril inhibits the reaction [Carbon Tetrachloride results in increased expression of AGTR1A protein] | PMID:12930639 PMID:16097048 | |
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