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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737162
Species: Homo sapiens
RGD Object: Gene
Symbol: SELP
Name: selectin P
Acc ID: CHEBI:16243
Term: quercetin
Definition: A pentahydroxyflavone having the five hydroxy groups placed at the 3-, 3'-, 4'-, 5- and 7-positions. It is one of the most abundant flavonoids in edible vegetables, fruit and wine.
Chemical ID: MESH:D011794
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SELPmultiple interactionsEXP 6480464CTDQuercetin inhibits the reaction [Adenosine Diphosphate results in increased expression of SELP protein]; Quercetin inhibits the reaction [Arachidonic Acid results in increased expression of SELP protein]; Quercetin inhibits the reaction [F2 protein results in increased expression of SELP protein]PMID:14628445 PMID:23249183
SELPmultiple interactionsISOSelp (Mus musculus)6480464CTDQuercetin inhibits the reaction [APOE gene mutant form results in increased expression of SELP protein]PMID:20093625
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