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GENE - TERM ANNOTATION REPORT

RGD ID: 737131
Species: Mus musculus
RGD Object: Gene
Symbol: Rapgef4
Name: Rap guanine nucleotide exchange factor (GEF) 4
Acc ID: GO:0030073
Term: insulin secretion
Definition: The regulated release of proinsulin from secretory granules accompanied by cleavage of proinsulin to form mature insulin. In vertebrates, insulin is secreted from B granules in the B cells of the vertebrate pancreas and from insulin-producing cells in insects.
Definition Source(s): GOC:mah, ISBN:0198506732
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rapgef4acts_upstream_of_or_withinIDA 2290270MGI PMID:11598134 PMID:12401793

PMID:11598134 PMID:12401793
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