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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737124
Species: Homo sapiens
RGD Object: Gene
Symbol: PDGFB
Name: platelet derived growth factor subunit B
Acc ID: CHEBI:135325
Term: mabuterol
Definition: null
Chemical ID: MESH:C044573
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PDGFBmultiple interactionsISOPdgfb (Rattus norvegicus)6480464CTD[mabuterol co-treated with 3-(2,4-dichloro-5-methoxyphenyl)-2-sulfanyl-4(3H)-quinazolinone] inhibits the reaction [[PDGFB protein co-treated with PDGFB protein] results in decreased expression of MFN2 mRNA]; [mabuterol co-treated with 3-(2,4-dichloro-5-methoxyphenyl)-2-sulfanyl-4(3H)-quinazolinone] inhibits the reaction [[PDGFB protein co-treated with PDGFB protein] results in decreased expression of MFN2 protein]; [mabuterol co-treated with 3-(2,4-dichloro-5-methoxyphenyl)-2-sulfanyl-4(3H)-quinazolinone] inhibits the reaction [[PDGFB protein co-treated with PDGFB protein] results in increased expression of CCND1 protein]; [mabuterol co-treated with 3-(2,4-dichloro-5-methoxyphenyl)-2-sulfanyl-4(3H)-quinazolinone] inhibits the reaction [[PDGFB protein co-treated with PDGFB protein] results in increased expression of DNM1L mRNA]; [mabuterol co-treated with 3-(2,4-dichloro-5-methoxyphenyl)-2-sulfanyl-4(3H)-quinazolinone] inhibits the reaction [[PDGFB protein co-treated with PDGFB protein] results in increased expression of DNM1L protein]; [mabuterol co-treated with 3-(2,4-dichloro-5-methoxyphenyl)-2-sulfanyl-4(3H)-quinazolinone] inhibits the reaction [[PDGFB protein co-treated with PDGFB protein] results in increased expression of PCNA protein]; mabuterol inhibits the reaction [[PDGFB protein co-treated with PDGFB protein] results in decreased expression of MFN2 mRNA]; mabuterol inhibits the reaction [[PDGFB protein co-treated with PDGFB protein] results in decreased expression of MFN2 protein]; mabuterol inhibits the reaction [[PDGFB protein co-treated with PDGFB protein] results in increased expression of CCND1 protein]; mabuterol inhibits the reaction [[PDGFB protein co-treated with PDGFB protein] results in increased expression of DNM1L mRNA]; mabuterol inhibits the reaction [[PDGFB protein co-treated with PDGFB protein] results in increased expression of DNM1L protein]; mabuterol inhibits the reaction [[PDGFB protein co-treated with PDGFB protein] results in increased expression of PCNA protein]PMID:31009640
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