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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737111
Species: Homo sapiens
RGD Object: Gene
Symbol: EGR1
Name: early growth response 1
Acc ID: CHEBI:7959
Term: D-penicillamine
Definition: An optically active form of penicillamine having D-configuration. Pharmaceutical form (L-form is toxic) of chelating agent used to treat heavy metal poisoning.
Chemical ID: MESH:D010396
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
EGR1increases expressionEXP 6480464CTDPenicillamine results in increased expression of EGR1 mRNAPMID:22843330
EGR1increases expressionISOEgr1 (Rattus norvegicus)6480464CTDPenicillamine results in increased expression of EGR1 mRNAPMID:19575532
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