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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737111
Species: Homo sapiens
RGD Object: Gene
Symbol: EGR1
Name: early growth response 1
Acc ID: CHEBI:29866
Term: arsenite(3-)
Definition: An arsenite ion resulting from the removal of all three protons from the hydroxy groups of arsenous acid.
Chemical ID: MESH:C015001
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
EGR1increases expressionEXP 6480464CTDarsenite results in increased expression of EGR1 mRNA; arsenite results in increased expression of EGR1 proteinPMID:23715767 PMID:32406909
EGR1multiple interactionsEXP 6480464CTDarsenite promotes the reaction [G3BP1 protein binds to EGR1 mRNA]PMID:32406909
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