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GENE - TERM ANNOTATION REPORT

RGD ID: 737102
Species: Homo sapiens
RGD Object: Gene
Symbol: COMT
Name: catechol-O-methyltransferase
Acc ID: GO:0016206
Term: catechol O-methyltransferase activity
Definition: Catalysis of the reaction: S-adenosyl-L-methionine + a catechol = S-adenosyl-L-homocysteine + a guaiacol.
Definition Source(s): EC:2.1.1.6
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
COMT ISOComt (Rattus norvegicus)9068941RGD PMID:12584150 REF_RGD_ID:1359089
COMTenablesIEAUniProtKB:O88587 or ensembl:ENSMUSP00000130077150520179Ensembl GO_REF:0000107
COMTenablesIBAMGI:3769724 or MGI:88470 or PANTHER:PTN000053580 or Comt (Rattus norvegicus) or UniProtKB:P21964 or ZFIN:ZDB-GENE-050913-117150520179GO_Central GO_REF:0000033
COMTenablesIEAInterPro:IPR017128150520179InterPro GO_REF:0000002
COMTenablesTAS 150520179Reactome Reactome:R-HSA-175983
COMTenablesIEAPANTHER:PTHR43836:SF3150520179TreeGrafter GO_REF:0000118
COMTenablesIDA 150520179UniProt PMID:11559542 PMID:15645182 PMID:21846718

PMID:11559542 PMID:15645182 PMID:21846718
COMTenablesIEAEC:2.1.1.6150520179UniProt GO_REF:0000003
COMTenablesIEAUniRule:UR000639763150520179UniProt GO_REF:0000104
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