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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737024
Species: Homo sapiens
RGD Object: Gene
Symbol: MUC5AC
Name: mucin 5AC, oligomeric mucus/gel-forming
Acc ID: CHEBI:47807
Term: sulforaphane
Definition: An isothiocyanate having a 4-(methylsulfinyl)butyl group attached to the nitrogen.
Chemical ID: MESH:C016766
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MUC5ACincreases expressionISOMuc5ac (Mus musculus)6480464CTDsulforaphane results in increased expression of MUC5AC mRNAPMID:30529165
MUC5ACmultiple interactionsISOMuc5ac (Mus musculus)6480464CTDNFE2L2 protein affects the reaction [sulforaphane inhibits the reaction [Oxygen results in increased secretion of MUC5AC protein]]; sulforaphane affects the reaction [NFE2L2 protein affects the secretion of MUC5AC protein]; sulforaphane inhibits the reaction [Oxygen results in increased secretion of MUC5AC protein]PMID:30529165
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