GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tlr4 | multiple interactions | EXP | | 6480464 | CTD | TLR4 affects the reaction [lipopolysaccharide, Escherichia coli O111 B4 inhibits the reaction [Glucose results in increased expression of INS2 mRNA alternative form]]; TLR4 affects the reaction [lipopolysaccharide, Escherichia coli O111 B4 inhibits the reaction [Glucose results in increased expression of MAFA mRNA]]; TLR4 affects the reaction [lipopolysaccharide, Escherichia coli O111 B4 inhibits the reaction [Glucose results in increased expression of PDX1 mRNA]] | PMID:22558381 | Tlr4 | decreases expression | ISO | TLR4 (Homo sapiens) | 6480464 | CTD | Glucose results in decreased expression of TLR4 protein | PMID:20200188 | Tlr4 | increases expression | ISO | Tlr4 (Rattus norvegicus) | 6480464 | CTD | Glucose results in increased expression of TLR4 protein | PMID:30031708 | Tlr4 | increases expression | ISO | TLR4 (Homo sapiens) | 6480464 | CTD | Glucose results in increased expression of TLR4 protein | PMID:38000455 | Tlr4 | multiple interactions | ISO | Tlr4 (Rattus norvegicus) | 6480464 | CTD | artesunate inhibits the reaction [Glucose results in increased expression of TLR4 protein] | PMID:30031708 | Tlr4 | multiple interactions | ISO | TLR4 (Homo sapiens) | 6480464 | CTD | Phytic Acid inhibits the reaction [Glucose results in increased expression of TLR4 protein] | PMID:38000455 | | ||||||||||||||||||||||
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