Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
[DDT co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of GJA1 protein; [Dieldrin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of GJA1 protein
2,4,5,2',4',5'-hexachlorobiphenyl promotes the reaction [MAPK1 protein results in increased phosphorylation of GJA1 protein]; 2,4,5,2',4',5'-hexachlorobiphenyl promotes the reaction [MAPK3 protein results in increased phosphorylation of GJA1 protein]; SPHK1 protein affects the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in decreased expression of GJA1 protein]