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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736867
Species: Mus musculus
RGD Object: Gene
Symbol: Abcc3
Name: ATP-binding cassette, sub-family C member 3
Acc ID: CHEBI:34674
Term: dextran sulfate
Definition: A polymer composed of repeating (1->6)-alpha-linked anhydroglucose sulfate units.
Chemical ID: MESH:D016264
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcc3affects response to substanceEXP 6480464CTDABCC3 protein affects the susceptibility to Dextran SulfatePMID:30701287
Abcc3decreases expressionEXP 6480464CTDDextran Sulfate results in decreased expression of ABCC3 mRNA; Dextran Sulfate results in decreased expression of ABCC3 proteinPMID:27580383
Abcc3multiple interactionsEXP 6480464CTD[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ABCC3 mRNA; ABCC3 protein affects the susceptibility to [Dextran Sulfate co-treated with 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine]PMID:29950665 PMID:30701287
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