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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736849
Species: Mus musculus
RGD Object: Gene
Symbol: Cox4i1
Name: cytochrome c oxidase subunit 4I1
Acc ID: CHEBI:27881
Term: resveratrol
Definition: A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups.
Chemical ID: MESH:C059514
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cox4i1decreases expressionEXP 6480464CTDresveratrol results in decreased expression of COX4I1 proteinPMID:25505154
Cox4i1increases expressionEXP 6480464CTDresveratrol results in increased expression of COX4I1 proteinPMID:24041027
Cox4i1multiple interactionsEXP 6480464CTDresveratrol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of COX4I1 protein]; tin protoporphyrin IX inhibits the reaction [resveratrol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of COX4I1 protein]]; tin protoporphyrin IX inhibits the reaction [resveratrol results in increased expression of COX4I1 protein]PMID:24041027
Cox4i1increases expressionISOCox4i1 (Rattus norvegicus)6480464CTDresveratrol results in increased expression of COX4I1 mRNA; resveratrol results in increased expression of COX4I1 proteinPMID:21715682
Cox4i1multiple interactionsISOCOX4I1 (Homo sapiens)6480464CTD1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one inhibits the reaction [resveratrol results in increased expression of COX4I1 protein]; HMOX1 mutant form inhibits the reaction [resveratrol results in increased expression of COX4I1 protein]; lipopolysaccharide, E coli O55-B5 promotes the reaction [resveratrol results in increased expression of COX4I1 protein]; resveratrol promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of COX4I1 protein]; tin protoporphyrin IX inhibits the reaction [lipopolysaccharide, E coli O55-B5 promotes the reaction [resveratrol results in increased expression of COX4I1 protein]]; tin protoporphyrin IX inhibits the reaction [resveratrol promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of COX4I1 protein]]; tin protoporphyrin IX inhibits the reaction [resveratrol results in increased expression of COX4I1 protein]PMID:24041027
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