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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736773
Species: Mus musculus
RGD Object: Gene
Symbol: Slc1a2
Name: solute carrier family 1 (glial high affinity glutamate transporter), member 2
Acc ID: CHEBI:28216
Term: methylmercury chloride
Definition: A chlorine molecular entity that has formula CH3ClHg.
Chemical ID: MESH:C004925
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc1a2decreases expressionISOSlc1a2 (Rattus norvegicus)6480464CTDmethylmercuric chloride results in decreased expression of SLC1A2 mRNAPMID:22966415
Slc1a2increases expressionISOSLC1A2 (Homo sapiens)6480464CTDmethylmercuric chloride results in increased expression of SLC1A2 mRNAPMID:23179753
Slc1a2multiple interactionsISOSlc1a2 (Rattus norvegicus)6480464CTDmethylmercuric chloride results in decreased expression of and results in decreased activity of SLC1A2 protein; Riluzole inhibits the reaction [methylmercuric chloride results in decreased expression of and results in decreased activity of SLC1A2 protein]; Riluzole inhibits the reaction [methylmercuric chloride results in decreased expression of SLC1A2 mRNA]PMID:22966415
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