Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736631
Species: Homo sapiens
RGD Object: Gene
Symbol: ITGB1
Name: integrin subunit beta 1
Acc ID: CHEBI:46666
Term: crocidolite asbestos
Definition: null
Chemical ID: MESH:D017638
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ITGB1decreases expressionISOItgb1 (Mus musculus)6480464CTDAsbestos, Crocidolite results in decreased expression of ITGB1 mRNAPMID:29279043
ITGB1multiple interactionsISOItgb1 (Rattus norvegicus)6480464CTDITGB1 protein affects the reaction [Asbestos, Crocidolite results in increased phosphorylation of AKT1 protein]; ITGB1 protein affects the reaction [Asbestos, Crocidolite results in increased phosphorylation of MAPK1 protein]; ITGB1 protein affects the reaction [Asbestos, Crocidolite results in increased phosphorylation of MAPK3 protein]PMID:14627993
Go Back to source page   Continue to Ontology report