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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736610
Species: Mus musculus
RGD Object: Gene
Symbol: Akr1b1
Name: aldo-keto reductase family 1 member B
Acc ID: CHEBI:82334
Term: (E,E)-2,4-hexadienal
Definition: A hexadienal that is hexanal with trans double bonds at positions 2 and 4. It is found in tomatoes, kiwi fruit, mangoes, potato chips, herbs and spices.
Chemical ID: MESH:C079389
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Akr1b1increases reductionISOAKR1B1 (Homo sapiens)6480464CTDAKR1B1 protein results in increased reduction of 2,4-hexadienal; AKR1B1 protein results in increased reduction of 2,4-hexadienal metabolitePMID:21329684 PMID:9890881
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