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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736525
Species: Homo sapiens
RGD Object: Gene
Symbol: IL6R
Name: interleukin 6 receptor
Acc ID: CHEBI:32509
Term: pirinixic acid
Definition: An aryl sulfide that has formula C14H14ClN3O2S.
Chemical ID: MESH:C006253
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IL6Rdecreases expressionISOIl6ra (Mus musculus)6480464CTDpirinixic acid results in decreased expression of IL6R mRNA; pirinixic acid results in decreased expression of IL6RA mRNAPMID:17321000 PMID:20813756 PMID:23811191
IL6Rmultiple interactionsISOIl6ra (Mus musculus)6480464CTDPPARA protein affects the reaction [pirinixic acid results in decreased expression of IL6R mRNA]PMID:17321000
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