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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736496
Species: Homo sapiens
RGD Object: Gene
Symbol: MAPT
Name: microtubule associated protein tau
Acc ID: CHEBI:16236
Term: ethanol
Definition: A primary alcohol that is ethane in which one of the hydrogens is substituted by a hydroxy group.
Chemical ID: MESH:D000431
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MAPTincreases phosphorylationISOMapt (Mus musculus)6480464CTDEthanol results in increased phosphorylation of MAPT proteinPMID:30143782
MAPTmultiple interactionsISOMapt (Mus musculus)6480464CTDEthanol affects the expression of and affects the splicing of MAPT mRNA; Roscovitine inhibits the reaction [Ethanol results in increased phosphorylation of MAPT protein]PMID:30143782 PMID:30319688
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