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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736488
Species: Homo sapiens
RGD Object: Gene
Symbol: CCNE1
Name: cyclin E1
Acc ID: CHEBI:18185
Term: gamma-tocopherol
Definition: A tocopherol in which the chroman-6-ol core is substituted by methyl groups at positions 7 and 8. It is found particularly in maize (corn) oil and soya bean (soybean) oils.
Chemical ID: MESH:D024505
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CCNE1decreases expressionEXP 6480464CTDgamma-Tocopherol results in decreased expression of CCNE1 mRNA; gamma-Tocopherol results in decreased expression of CCNE1 protein; Tocopherols results in decreased expression of CCNE1 mRNA; Tocopherols results in decreased expression of CCNE1 proteinPMID:12368234 PMID:12504091 PMID:31587439
CCNE1multiple interactionsEXP 6480464CTD[Fluorouracil co-treated with gamma-Tocopherol] results in decreased expression of CCNE1 mRNAPMID:31587439
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