GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Sqstm1 | increases expression | EXP | | 6480464 | CTD | bisphenol A results in increased expression of SQSTM1 mRNA; bisphenol A results in increased expression of SQSTM1 protein | PMID:12233820 PMID:33221593 PMID:34186417 PMID:34281243 PMID:35357751 | Sqstm1 | multiple interactions | EXP | | 6480464 | CTD | [bisphenol A co-treated with 9-(6-aminopyridin-3-yl)-1-(3-(trifluoromethyl)phenyl)benzo(h)(1,6)naphthyridin-2(1H)-one] results in increased expression of SQSTM1 protein; [bisphenol A co-treated with Chloroquine] results in increased expression of SQSTM1 protein | PMID:34186417 | Sqstm1 | affects expression | ISO | Sqstm1 (Rattus norvegicus) | 6480464 | CTD | bisphenol A affects the expression of SQSTM1 mRNA | PMID:25181051 PMID:30903817 | Sqstm1 | affects expression | ISO | SQSTM1 (Homo sapiens) | 6480464 | CTD | bisphenol A affects the expression of SQSTM1 mRNA | PMID:30903817 | Sqstm1 | decreases expression | ISO | Sqstm1 (Rattus norvegicus) | 6480464 | CTD | bisphenol A analog results in decreased expression of SQSTM1 mRNA; bisphenol A analog results in decreased expression of SQSTM1 protein | PMID:35427877 | Sqstm1 | decreases expression | ISO | SQSTM1 (Homo sapiens) | 6480464 | CTD | bisphenol A results in decreased expression of SQSTM1 mRNA; bisphenol A results in decreased expression of SQSTM1 protein | PMID:16474171 PMID:34186270 | Sqstm1 | increases expression | ISO | Sqstm1 (Rattus norvegicus) | 6480464 | CTD | bisphenol A results in increased expression of SQSTM1 protein | PMID:31551937 | Sqstm1 | increases expression | ISO | SQSTM1 (Homo sapiens) | 6480464 | CTD | bisphenol A results in increased expression of SQSTM1 mRNA; bisphenol A results in increased expression of SQSTM1 protein | PMID:29275510 PMID:34281243 | Sqstm1 | increases methylation | ISO | Sqstm1 (Rattus norvegicus) | 6480464 | CTD | bisphenol A results in increased methylation of SQSTM1 gene | PMID:28505145 | Sqstm1 | multiple interactions | ISO | Sqstm1 (Rattus norvegicus) | 6480464 | CTD | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of SQSTM1 mRNA | PMID:36041667 | Sqstm1 | multiple interactions | ISO | SQSTM1 (Homo sapiens) | 6480464 | CTD | [3-methyladenine co-treated with bisphenol A] results in increased expression of SQSTM1 protein; [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of SQSTM1 mRNA | PMID:28628672 PMID:34281243 | | ||||||||||||||||||||||
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