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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736458
Species: Homo sapiens
RGD Object: Gene
Symbol: TFF3
Name: trefoil factor 3
Acc ID: CHEBI:10022
Term: deoxynivalenol
Definition: A trichothecene mycotoxin produced by Fusarium to which wheat, barley, maize (corn) and their products are susceptible to contamination.
Chemical ID: MESH:C007262
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
TFF3affects expressionEXP 6480464CTDdeoxynivalenol affects the expression of TFF3 mRNAPMID:30854615
TFF3decreases secretionEXP 6480464CTDdeoxynivalenol results in decreased secretion of TFF3 proteinPMID:30854615
TFF3multiple interactionsEXP 6480464CTD2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one affects the reaction [deoxynivalenol affects the expression of TFF3 mRNA]; Adenine affects the reaction [deoxynivalenol affects the expression of TFF3 mRNA]; SB 203580 affects the reaction [deoxynivalenol affects the expression of TFF3 mRNA]PMID:30854615
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