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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736399
Species: Mus musculus
RGD Object: Gene
Symbol: Hspa1b
Name: heat shock protein 1B
Acc ID: CHEBI:30621
Term: diarsenic trioxide
Definition: An arsenic oxide in which arsenic and oxygen atoms are present in the ratio 2:3.
Chemical ID: MESH:C006632
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hspa1baffects expressionISOHSPA1B (Homo sapiens)6480464CTDArsenic Trioxide affects the expression of HSPA1B mRNAPMID:17530438
Hspa1baffects response to substanceISOHSPA1B (Homo sapiens)6480464CTDHSPA1B protein affects the susceptibility to Arsenic TrioxidePMID:19371599
Hspa1bincreases expressionISOHSPA1B (Homo sapiens)6480464CTDArsenic Trioxide results in increased expression of HSPA1B mRNAPMID:19417148 PMID:23824090 PMID:24356939 PMID:25258189 PMID:27829220
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