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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736398
Species: Homo sapiens
RGD Object: Gene
Symbol: HSPA1B
Name: heat shock protein family A (Hsp70) member 1B
Acc ID: CHEBI:29678
Term: sodium arsenite
Definition: An inoganic sodium salt with formula with formula NaAsO2.
Chemical ID: MESH:C017947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
HSPA1Baffects methylationEXP 6480464CTDsodium arsenite affects the methylation of HSPA1B genePMID:28589171
HSPA1Bincreases expressionEXP 6480464CTDsodium arsenite results in increased expression of HSPA1B mRNAPMID:10544156 PMID:24516582 PMID:36586010
HSPA1Bincreases expressionISOHspa1b (Mus musculus)6480464CTDsodium arsenite results in increased expression of HSPA1B mRNA; sodium arsenite results in increased expression of HSPA1B proteinPMID:11353140 PMID:12085988 PMID:15327774 PMID:16322246 PMID:17682005 PMID:18812580 PMID:22700541
HSPA1Bmultiple interactionsISOHspa1b (Mus musculus)6480464CTD[sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in decreased expression of HSPA1B mRNAPMID:34876320
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