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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736398
Species: Homo sapiens
RGD Object: Gene
Symbol: HSPA1B
Name: heat shock protein family A (Hsp70) member 1B
Acc ID: CHEBI:25812
Term: ozone
Definition: An elemental molecule with formula O3. An explosive, pale blue gas (b.p. -112degreeC) that has a characteristic, pungent odour, it is continuously produced in the upper atmosphere by the action of solar ultraviolet radiation on atmospheric oxygen. It is an antimicrobial agent used in the production of bottled water, as well as in the treatment of meat, poultry and other foodstuffs.
Chemical ID: MESH:D010126
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
HSPA1Bmultiple interactionsEXP 6480464CTD[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of HSPA1B mRNA; [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased expression of HSPA1B mRNA; [Volatile Organic Compounds co-treated with Ozone] results in increased expression of HSPA1B mRNAPMID:32699268
HSPA1Bincreases expressionISOHspa1b (Mus musculus)6480464CTDOzone results in increased expression of HSPA1B mRNA; Ozone results in increased expression of HSPA1B proteinPMID:20032013 PMID:21543283
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