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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736217
Species: Homo sapiens
RGD Object: Gene
Symbol: CYP2D6
Name: cytochrome P450 family 2 subfamily D member 6
Acc ID: CHEBI:166520
Term: 3,4-Methylenedioxyamphetamine
Definition: null
Chemical ID: MESH:D015104
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CYP2D6multiple interactionsEXP 6480464CTD[CYP2D6 protein results in increased metabolism of and results in decreased methylation of 3,4-Methylenedioxyamphetamine] which results in increased chemical synthesis of alpha-methyldopamine; CYP2D6 protein results in increased metabolism of and results in decreased methylation of 3,4-MethylenedioxyamphetaminePMID:19576971
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