A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID:
MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CEBPB protein]; [NFE2L2 gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in increased expression of CEBPB mRNA; [Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in increased expression of CEBPB mRNA; [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CEBPB mRNA; CEBPB protein inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of SLC2A4 mRNA]; CREB1 protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CEBPB mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CEBPB mRNA]; SRC protein promotes the reaction [Tetrachlorodibenzodioxin results in decreased expression of CEBPB mRNA]; SRC protein promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of CEBPB protein]; SRC protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CEBPB mRNA]; Tetrachlorodibenzodioxin promotes the reaction [CEBPB protein binds to SLC2A4 promoter]; Tetrachlorodibenzodioxin promotes the reaction [CREB1 protein binds to CEBPB promoter]; Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CEBPB protein; TGFA gene mutant form inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CEBPB mRNA]
geldanamycin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of [[CEBPB protein binds to CEBPB protein] which binds to PTGS2 promoter]]; herbimycin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of [[CEBPA protein binds to CEBPB protein] which binds to PTGS2 promoter]]; Tetrachlorodibenzodioxin promotes the reaction [CEBPB protein binds to IGF2 promoter]; Tetrachlorodibenzodioxin results in increased activity of [[CEBPA protein binds to CEBPB protein] which binds to PTGS2 promoter]; Tetrachlorodibenzodioxin results in increased activity of [[CEBPB protein binds to CEBPB protein] which binds to PTGS2 promoter]
