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GENE - TERM ANNOTATION REPORT

RGD ID: 736187
Species: Homo sapiens
RGD Object: Gene
Symbol: PRL
Name: prolactin
Acc ID: GO:0005179
Term: hormone activity
Definition: The action characteristic of a hormone, any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action. The term was originally applied to agents with a stimulatory physiological action in vertebrate animals (as opposed to a chalone, which has a depressant action). Usage is now extended to regulatory compounds in lower animals and plants, and to synthetic substances having comparable effects; all bind receptors and trigger some biological process.
Definition Source(s): GOC:dph, GOC:mah, ISBN:0198506732
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PRLenablesIBAMGI:1341833 or MGI:97618 or MGI:97619 or PANTHER:PTN000151829 or Gh1 (Rattus norvegicus) or ZFIN:ZDB-GENE-030725-2150520179GO_Central GO_REF:0000033
PRLenablesIEAInterPro:IPR001400 or InterPro:IPR018116150520179InterPro GO_REF:0000002
PRLenablesIEAPANTHER:PTHR11417:SF5150520179TreeGrafter GO_REF:0000118
PRLenablesIEAUniProtKB-KW:KW-0372150520179UniProt GO_REF:0000043
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