GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | PRL | decreases expression | EXP | | 6480464 | CTD | 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of PRL mRNA; 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of PRL protein | PMID:18815356 | PRL | increases expression | EXP | | 6480464 | CTD | 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PRL mRNA; 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PRL protein | PMID:15774544 PMID:17065600 PMID:20147733 PMID:20955787 PMID:23275455 | PRL | increases secretion | EXP | | 6480464 | CTD | 8-Bromo Cyclic Adenosine Monophosphate results in increased secretion of PRL protein | PMID:21273127 | PRL | multiple interactions | EXP | | 6480464 | CTD | 1-Butanol inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PRL mRNA]; [8-Bromo Cyclic Adenosine Monophosphate co-treated with Dexamethasone] results in increased expression of PRL mRNA; [8-Bromo Cyclic Adenosine Monophosphate co-treated with Medroxyprogesterone Acetate] results in increased expression of PRL mRNA; [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased secretion of PRL protein; EZH2 mutant form inhibits the reaction [[8-Bromo Cyclic Adenosine Monophosphate co-treated with Medroxyprogesterone Acetate] results in increased expression of PRL mRNA]; FOXO1 protein affects the reaction [[Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased secretion of PRL protein]; PLD1 protein affects the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PRL mRNA]; Progesterone promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PRL mRNA]; Tobacco Smoke Pollution inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PRL mRNA] | PMID:16709600 PMID:17065600 PMID:20955787 PMID:21903722 PMID:23275455 | PRL | increases expression | ISO | Prl (Rattus norvegicus) | 6480464 | CTD | 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PRL mRNA | PMID:21467749 | |
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