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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736179
Species: Mus musculus
RGD Object: Gene
Symbol: Scn10a
Name: sodium channel, voltage-gated, type X, alpha
Acc ID: CHEBI:6736
Term: melittin
Definition: A 26-membered polypeptide consisting of Gly, Ile, Gly, Ala, Val, Leu, Lys, Val, Leu, Thr, Thr, Gly, Leu, Pro, Ala, Leu, Ile, Ser, Trp, Ile, Lys, Arg, Lys, Arg, Gln and Gln-NH2 residues joined in sequence. It is the principal active component of bee venom.
Chemical ID: MESH:D008555
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Scn10aincreases expressionISOScn10a (Rattus norvegicus)6480464CTDMelitten results in increased expression of SCN10A mRNA; Melitten results in increased expression of SCN10A proteinPMID:23264124
Scn10amultiple interactionsISOScn10a (Rattus norvegicus)6480464CTD[Melitten results in increased expression of SCN10A protein] which results in increased transport of SodiumPMID:23264124
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