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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736172
Species: Homo sapiens
RGD Object: Gene
Symbol: SHBG
Name: sex hormone binding globulin
Acc ID: CHEBI:6443
Term: levonorgestrel
Definition: A terminal acetylenic compound that has formula C21H28O2.
Chemical ID: MESH:D016912
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SHBGaffects bindingEXP 6480464CTDLevonorgestrel binds to SHBG proteinPMID:12586319
SHBGmultiple interactionsEXP 6480464CTD[Ethinyl Estradiol co-treated with Levonorgestrel] results in increased expression of SHBG proteinPMID:12586319 PMID:14981370 PMID:17519148
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