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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736136
Species: Homo sapiens
RGD Object: Gene
Symbol: ASS1
Name: argininosuccinate synthase 1
Acc ID: CHEBI:15367
Term: all-trans-retinoic acid
Definition: A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry.
Chemical ID: MESH:D014212
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ASS1decreases expressionEXP 6480464CTDTretinoin results in decreased expression of ASS1 mRNAPMID:12875902 PMID:15894607 PMID:16129123 PMID:21934132 PMID:33167477
ASS1multiple interactionsEXP 6480464CTD[Tretinoin co-treated with arsenic trioxide] results in decreased expression of ASS1 mRNAPMID:15894607
ASS1multiple interactionsISOAss1 (Mus musculus)6480464CTD[bisphenol A co-treated with Tretinoin] results in decreased expression of ASS1 mRNA; [bisphenol F co-treated with Tretinoin] results in decreased expression of ASS1 mRNA; [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of ASS1 mRNAPMID:30951980 PMID:36189433
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