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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736070
Species: Homo sapiens
RGD Object: Gene
Symbol: PDGFA
Name: platelet derived growth factor subunit A
Acc ID: CHEBI:46680
Term: serpentine asbestos
Definition: null
Chemical ID: MESH:D017632
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PDGFAincreases expressionISOPdgfa (Mus musculus)6480464CTDAsbestos, Serpentine results in increased expression of PDGFA mRNAPMID:18039278 PMID:9846974
PDGFAincreases expressionISOPdgfa (Rattus norvegicus)6480464CTDAsbestos, Serpentine results in increased expression of PDGFA mRNA; Asbestos, Serpentine results in increased expression of PDGFA proteinPMID:9271299
PDGFAmultiple interactionsISOPdgfa (Mus musculus)6480464CTD[TNFRSF1A gene mutant form co-treated with TNFRSF1B gene mutant form] inhibits the reaction [Asbestos, Serpentine results in increased expression of PDGFA mRNA]PMID:9846974
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