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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736070
Species: Homo sapiens
RGD Object: Gene
Symbol: PDGFA
Name: platelet derived growth factor subunit A
Acc ID: CHEBI:15379
Term: dioxygen
Definition: An elemental molecule that has formula O2.
Chemical ID: MESH:D010100
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PDGFAincreases expressionEXP 6480464CTDOxygen deficiency results in increased expression of PDGFA mRNAPMID:24403227
PDGFAmultiple interactionsEXP 6480464CTD1-cyclopropyl-4-(4-((5-methyl-3-(3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazol-5-yl)-1H-pyrazol-1-yl)methyl)pyridin-2-yl)piperazine inhibits the reaction [Oxygen deficiency results in increased expression of PDGFA mRNA]PMID:24403227
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