GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mapk9 | decreases expression | ISO | MAPK9 (Homo sapiens) | 6480464 | CTD | Doxorubicin results in decreased expression of MAPK9 mRNA | PMID:29803840 | Mapk9 | increases phosphorylation | ISO | Mapk9 (Rattus norvegicus) | 6480464 | CTD | Doxorubicin results in increased phosphorylation of MAPK9 protein | PMID:16213474 PMID:17384285 PMID:26335259 PMID:35843304 | Mapk9 | increases phosphorylation | ISO | MAPK9 (Homo sapiens) | 6480464 | CTD | Doxorubicin results in increased phosphorylation of MAPK9 protein | PMID:15557793 PMID:15585644 PMID:31563593 | Mapk9 | multiple interactions | ISO | Mapk9 (Rattus norvegicus) | 6480464 | CTD | [Taurine binds to Zinc] inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK9 protein]; Doxorubicin results in increased phosphorylation of and results in increased activity of MAPK9 protein; galangin inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK9 protein]; pifithrin inhibits the reaction [Doxorubicin results in increased phosphorylation of and results in increased activity of MAPK9 protein]; Taurine inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK9 protein] | PMID:16687611 PMID:26335259 PMID:35843304 | Mapk9 | multiple interactions | ISO | MAPK9 (Homo sapiens) | 6480464 | CTD | 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK9 protein]; [Doxorubicin co-treated with 2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid] results in increased phosphorylation of MAPK9 protein; Doxorubicin results in increased phosphorylation of and results in increased activity of MAPK9 protein; pyrrolidine dithiocarbamic acid inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK9 protein]; RBL2 protein inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK9 protein] | PMID:15494689 PMID:15557793 PMID:15585644 PMID:21214929 | |
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