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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736023
Species: Homo sapiens
RGD Object: Gene
Symbol: MAPK9
Name: mitogen-activated protein kinase 9
Acc ID: CHEBI:78782
Term: pyrrolidine dithiocarbamate
Definition: A member of the class of dithiocarbamic acids that is the N-dithiocarboxy derivative of pyrrolidine.
Chemical ID: MESH:C020972
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MAPK9multiple interactionsEXP 6480464CTDpyrrolidine dithiocarbamic acid inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK9 protein]PMID:15557793
MAPK9multiple interactionsISOMapk9 (Rattus norvegicus)6480464CTD[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK9 protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK9 protein]; pyrazolanthrone inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK9 protein]PMID:22085843
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