GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | App | decreases secretion | EXP | | 6480464 | CTD | APP protein results in decreased secretion of Acetylcholine | PMID:16122837 | App | multiple interactions | EXP | | 6480464 | CTD | [IL1B protein co-treated with APP protein] results in increased secretion of Acetylcholine; IL1B protein inhibits the reaction [APP protein results in decreased secretion of Acetylcholine] | PMID:16122837 | App | multiple interactions | ISO | App (Rattus norvegicus) | 6480464 | CTD | APP protein modified form inhibits the reaction [Nicotine results in increased secretion of Acetylcholine]; spiro(imidazo-(1,2-a)pyridine-3,2-indan)-2(3H)-one inhibits the reaction [APP protein modified form inhibits the reaction [Nicotine results in increased secretion of Acetylcholine]] | PMID:16474004 | App | multiple interactions | ISO | APP (Homo sapiens) | 6480464 | CTD | GW 501516 inhibits the reaction [APP gene mutant form results in decreased susceptibility to Acetylcholine] | PMID:22886847 | | ||||||||||||||||||||||
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