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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735962
Species: Homo sapiens
RGD Object: Gene
Symbol: APOA1
Name: apolipoprotein A1
Acc ID: CHEBI:42839
Term: 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine
Definition: Puromycin derivative that lacks the methoxyphenylalanyl group on the amine of the sugar ring.
Chemical ID: MESH:D011692
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
APOA1decreases response to substanceEXP 6480464CTDAPOA1 protein results in decreased susceptibility to Puromycin AminonucleosidePMID:7595070
APOA1increases expressionEXP 6480464CTDPuromycin Aminonucleoside results in increased expression of APOA1 mRNAPMID:7595070
APOA1increases expressionISOApoa1 (Rattus norvegicus)6480464CTDPuromycin Aminonucleoside results in increased expression of APOA1 mRNA; Puromycin Aminonucleoside results in increased expression of APOA1 proteinPMID:7066357 PMID:7442475 PMID:7595070 PMID:8412754 PMID:8413767 PMID:8506949 PMID:9059516
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