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GENE - TERM ANNOTATION REPORT

RGD ID: 735930
Species: Mus musculus
RGD Object: Gene
Symbol: Pias2
Name: protein inhibitor of activated STAT 2
Acc ID: GO:0061665
Term: SUMO ligase activity
Definition: Catalysis of the transfer of SUMO to a substrate protein via the reaction X-SUMO + S = X + S-SUMO, where X is either an E2 or E3 enzyme, the X-SUMO linkage is a thioester bond, and the S-SUMO linkage is an isopeptide bond between the C-terminal amino acid of SUMO and the epsilon-amino group of lysine residues in the substrate.
Definition Source(s): GOC:dph
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pias2enablesIBAPANTHER:PTN000081660 or MGI:2136940 or FB:FBgn0003612 or PomBase:SPAC1687.05 or UniProtKB:Q6ASW7 or UniProtKB:O75928 or WB:WBGene00001574 or UniProtKB:Q8N2W9 or MGI:1913125 or CGD:CAL0000192524 or UniProtKB:O75925 or UniProtKB:Q6L4L42290270GO_Central GO_REF:0000033
Pias2enablesISOUniProtKB:O759282290270MGI GO_REF:0000119 MGI:4834177
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