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GENE - TERM ANNOTATION REPORT

RGD ID: 735920
Species: Mus musculus
RGD Object: Gene
Symbol: Fmr1
Name: fragile X messenger ribonucleoprotein 1
Acc ID: GO:0043197
Term: dendritic spine
Definition: A small, membranous protrusion from a dendrite that forms a postsynaptic compartment, typically receiving input from a single presynapse. They function as partially isolated biochemical and an electrical compartments. Spine morphology is variable:they can be thin, stubby, mushroom, or branched, with a continuum of intermediate morphologies. They typically terminate in a bulb shape, linked to the dendritic shaft by a restriction. Spine remodeling is though to be involved in synaptic plasticity.
Definition Source(s): GOC:nln
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fmr1located_inISOFmr1 (Rattus norvegicus)2290270MGI GO_REF:0000096 MGI:4417868
Fmr1located_inIDA 2290270UniProt MGI:3655188 PMID:16631377 MGI:3798322 PMID:18539120

MGI:3655188 MGI:3798322 PMID:16631377 PMID:18539120
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