GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | IL17A | decreases expression | EXP | | 6480464 | CTD | triptolide results in decreased expression of IL17A mRNA | PMID:38115356 | IL17A | increases expression | ISO | Il17a (Mus musculus) | 6480464 | CTD | triptolide results in increased expression of IL17A mRNA; triptolide results in increased expression of IL17A protein | PMID:24949944 PMID:36520315 | IL17A | multiple interactions | ISO | Il17a (Mus musculus) | 6480464 | CTD | IL17A protein promotes the reaction [triptolide results in increased expression of CCL11 mRNA]; IL17A protein promotes the reaction [triptolide results in increased expression of CXCL1 mRNA]; IL17A protein promotes the reaction [triptolide results in increased expression of CXCL2 mRNA]; IL17A protein promotes the reaction [triptolide results in increased expression of FASL mRNA]; IL17A protein promotes the reaction [triptolide results in increased expression of IL1B mRNA] | PMID:24949944 | | ||||||||||||||||||||||
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