GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | IL17A | affects response to substance | ISO | Il17a (Mus musculus) | 6480464 | CTD | IL17A protein affects the susceptibility to Dextran Sulfate | PMID:21068411 | IL17A | increases expression | ISO | Il17a (Mus musculus) | 6480464 | CTD | Dextran Sulfate results in increased expression of IL17A mRNA; Dextran Sulfate results in increased expression of IL17A protein | PMID:24384223 PMID:24548422 PMID:26074695 PMID:26973525 PMID:27995407 PMID:29672155 PMID:31737179 PMID:31807802 PMID:33130971 PMID:34998820 | IL17A | increases expression | ISO | Il17a (Rattus norvegicus) | 6480464 | CTD | Dextran Sulfate results in increased expression of IL17A mRNA | PMID:20881082 | IL17A | multiple interactions | ISO | Il17a (Mus musculus) | 6480464 | CTD | 2-(1'H-indole-3'-carbonyl)thiazole-4-carboxylic acid methyl ester inhibits the reaction [Dextran Sulfate results in increased expression of IL17A protein]; [IL17A protein affects the susceptibility to Dextran Sulfate] which affects the expression of IFNG protein; [IL17A protein affects the susceptibility to Dextran Sulfate] which affects the expression of IL1B protein; [IL17A protein affects the susceptibility to Dextran Sulfate] which affects the expression of IL6 protein; [IL17A protein affects the susceptibility to Dextran Sulfate] which affects the expression of TNF protein; [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of IL17A mRNA; [TNFRSF8 protein affects the susceptibility to Dextran Sulfate] which affects the secretion of IL17A protein; [TNFSF8 protein affects the susceptibility to Dextran Sulfate] which affects the secretion of IL17A protein; ADAM17 protein affects the reaction [Dextran Sulfate results in increased expression of IL17A protein]; AHR gene mutant form promotes the reaction [Dextran Sulfate results in increased expression of IL17A mRNA]; Benzo(a)pyrene inhibits the reaction [Dextran Sulfate results in increased expression of IL17A mRNA]; celastrol inhibits the reaction [Dextran Sulfate results in increased expression of IL17A protein]; geraniol inhibits the reaction [Dextran Sulfate results in increased expression of IL17A protein]; HU 211 inhibits the reaction [Dextran Sulfate results in increased expression of IL17A protein]; ligustilide inhibits the reaction [Dextran Sulfate results in increased expression of IL17A mRNA]; Mesalamine inhibits the reaction [Dextran Sulfate results in increased expression of IL17A mRNA]; Qingdai compound inhibits the reaction [Dextran Sulfate results in increased expression of IL17A mRNA]; Qingdai compound inhibits the reaction [Dextran Sulfate results in increased expression of IL17A protein]; Resveratrol inhibits the reaction [Dextran Sulfate results in increased expression of IL17A protein]; TLR4 protein affects the reaction [HU 211 inhibits the reaction [Dextran Sulfate results in increased expression of IL17A protein]] | PMID:21068411 PMID:24384223 PMID:24548422 PMID:26074695 PMID:26973525 PMID:27995407 PMID:29672155 PMID:29950665 PMID:31737179 PMID:33130971 PMID:34998820 PMID:36519841 | IL17A | multiple interactions | ISO | Il17a (Rattus norvegicus) | 6480464 | CTD | kappa-casein glycomacropeptide inhibits the reaction [Dextran Sulfate results in increased expression of IL17A mRNA] | PMID:20881082 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |