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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735879
Species: Mus musculus
RGD Object: Gene
Symbol: Ache
Name: acetylcholinesterase
Acc ID: CHEBI:82142
Term: Mipafox
Definition: A phosphoramide that has formula C6H16FN2OP.
Chemical ID: MESH:C005238
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Achedecreases activityEXP 6480464CTDmipafox results in decreased activity of ACHE proteinPMID:24395470 PMID:9268605 PMID:9515941
Achedecreases activityISOAche (Rattus norvegicus)6480464CTDmipafox results in decreased activity of ACHE proteinPMID:7713347
Achedecreases activityISOACHE (Homo sapiens)6480464CTDmipafox results in decreased activity of ACHE proteinPMID:16766477 PMID:24395470 PMID:25743373 PMID:9268605 PMID:9515941
Achemultiple interactionsISOACHE (Homo sapiens)6480464CTDMetoclopramide inhibits the reaction [mipafox binds to and results in decreased activity of ACHE protein]; Metoclopramide inhibits the reaction [mipafox results in decreased activity of ACHE protein]; mipafox binds to and results in decreased activity of ACHE proteinPMID:14635269 PMID:15052610 PMID:16193528
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