GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ache | decreases activity | EXP | | 6480464 | CTD | Methyl Parathion results in decreased activity of ACHE protein | PMID:29540303 PMID:32294493 PMID:9588345 | Ache | decreases activity | ISO | Ache (Rattus norvegicus) | 6480464 | CTD | Methyl Parathion results in decreased activity of ACHE protein | PMID:10918524 PMID:11405414 PMID:11481665 PMID:11495289 PMID:12478623 PMID:14514956 PMID:1455421 PMID:14746346 PMID:15342957 PMID:15591769 PMID:15793557 PMID:16645783 PMID:19784758 PMID:20100039 PMID:2241428 PMID:3247000 PMID:3975908 PMID:6483827 PMID:7322183 PMID:7966439 | Ache | decreases activity | ISO | ACHE (Homo sapiens) | 6480464 | CTD | Methyl Parathion results in decreased activity of ACHE protein | PMID:12191869 PMID:16766477 | Ache | multiple interactions | ISO | Ache (Rattus norvegicus) | 6480464 | CTD | [Methyl Parathion co-treated with Chlorpyrifos] results in decreased activity of ACHE protein; [Methyl Parathion co-treated with NADP] results in decreased activity of ACHE protein; [Methyl Parathion co-treated with pralidoxime co-treated with Atropine] results in decreased expression of ACHE protein; [Methyl Parathion co-treated with pralidoxime] results in decreased expression of ACHE protein; Atropine inhibits the reaction [Methyl Parathion results in decreased activity of ACHE protein]; CYP2B1 protein affects the reaction [Methyl Parathion results in decreased activity of ACHE protein]; CYP2B2 protein affects the reaction [Methyl Parathion results in decreased activity of ACHE protein]; Glutathione inhibits the reaction [Methyl Parathion results in decreased activity of ACHE protein]; Memantine inhibits the reaction [Methyl Parathion results in decreased activity of ACHE protein]; Phenobarbital inhibits the reaction [Methyl Parathion results in decreased activity of ACHE protein] | PMID:11405414 PMID:11684353 PMID:17963125 PMID:20100039 PMID:2241428 | Ache | multiple interactions | ISO | ACHE (Homo sapiens) | 6480464 | CTD | [Methyl Parathion co-treated with decamethrin] results in decreased activity of ACHE protein; [Methyl Parathion co-treated with Parathion] results in decreased activity of ACHE protein | PMID:12191869 PMID:1512808 | | ||||||||||||||||||||||
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