GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ache | decreases activity | EXP | | 6480464 | CTD | bisphenol A results in decreased activity of ACHE protein | PMID:23871786 PMID:34655688 | Ache | decreases expression | EXP | | 6480464 | CTD | bisphenol A results in decreased expression of ACHE mRNA | PMID:32156529 | Ache | increases expression | EXP | | 6480464 | CTD | bisphenol A results in increased expression of ACHE mRNA; bisphenol A results in increased expression of ACHE mRNA alternative form | PMID:34655688 | Ache | multiple interactions | EXP | | 6480464 | CTD | HDAC2 protein affects the reaction [bisphenol A results in increased expression of ACHE mRNA alternative form]; HDAC2 protein affects the reaction [bisphenol A results in increased expression of ACHE mRNA] | PMID:34655688 | Ache | decreases expression | ISO | Ache (Rattus norvegicus) | 6480464 | CTD | bisphenol A results in decreased expression of ACHE mRNA | PMID:25181051 PMID:30816183 PMID:32528016 PMID:34947998 | Ache | increases activity | ISO | Ache (Rattus norvegicus) | 6480464 | CTD | bisphenol A results in increased activity of ACHE protein | PMID:32172062 PMID:32701268 PMID:32810514 | Ache | increases activity | ISO | ACHE (Homo sapiens) | 6480464 | CTD | bisphenol A results in increased activity of ACHE protein | PMID:29079494 | Ache | increases expression | ISO | Ache (Rattus norvegicus) | 6480464 | CTD | bisphenol A results in increased expression of ACHE protein | PMID:32428650 | Ache | increases expression | ISO | ACHE (Homo sapiens) | 6480464 | CTD | bisphenol A results in increased expression of ACHE mRNA; bisphenol A results in increased expression of ACHE protein | PMID:30238673 | Ache | increases methylation | ISO | ACHE (Homo sapiens) | 6480464 | CTD | bisphenol A results in increased methylation of ACHE gene | PMID:28582417 | Ache | multiple interactions | ISO | Ache (Rattus norvegicus) | 6480464 | CTD | [NG-Nitroarginine Methyl Ester co-treated with bisphenol A co-treated with naringin] results in increased expression of ACHE protein; [NG-Nitroarginine Methyl Ester co-treated with bisphenol A] results in increased activity of ACHE protein; [NG-Nitroarginine Methyl Ester co-treated with bisphenol A] results in increased expression of ACHE protein; bisphenol A promotes the reaction [NG-Nitroarginine Methyl Ester results in increased expression of ACHE protein]; naringin inhibits the reaction [[NG-Nitroarginine Methyl Ester co-treated with bisphenol A] results in increased activity of ACHE protein]; naringin inhibits the reaction [[NG-Nitroarginine Methyl Ester co-treated with bisphenol A] results in increased expression of ACHE protein]; naringin inhibits the reaction [bisphenol A results in increased activity of ACHE protein]; NG-Nitroarginine Methyl Ester promotes the reaction [bisphenol A results in increased expression of ACHE protein] | PMID:32172062 PMID:32428650 PMID:32810514 | |
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