GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ache | decreases expression | EXP | | 6480464 | CTD | Sodium Fluoride results in decreased expression of ACHE mRNA; Sodium Fluoride results in decreased expression of ACHE protein | PMID:27862939 PMID:36286330 | Ache | increases activity | EXP | | 6480464 | CTD | Sodium Fluoride results in increased activity of ACHE protein | PMID:19635623 | Ache | multiple interactions | EXP | | 6480464 | CTD | Choline inhibits the reaction [Sodium Fluoride results in decreased expression of ACHE protein]; sodium arsenite promotes the reaction [Sodium Fluoride results in increased activity of ACHE protein] | PMID:19635623 PMID:36286330 | Ache | affects activity | ISO | Ache (Rattus norvegicus) | 6480464 | CTD | Sodium Fluoride affects the activity of ACHE protein | PMID:36228752 | Ache | decreases activity | ISO | Ache (Rattus norvegicus) | 6480464 | CTD | Sodium Fluoride results in decreased activity of ACHE protein | PMID:27840156 PMID:31710167 | Ache | multiple interactions | ISO | Ache (Rattus norvegicus) | 6480464 | CTD | [2,2-bis(4-glycidyloxyphenyl)propane co-treated with Hesperidin] inhibits the reaction [[Sodium Fluoride results in increased abundance of Fluorides] which results in increased activity of ACHE protein]; [[sodium arsenite results in increased abundance of Arsenic] co-treated with [Sodium Fluoride results in increased abundance of Fluorides]] results in decreased activity of ACHE protein; [Sodium Fluoride results in increased abundance of Fluorides] which results in increased activity of ACHE protein; Clofibrate inhibits the reaction [Sodium Fluoride results in decreased activity of ACHE protein]; Hesperidin inhibits the reaction [[Sodium Fluoride results in increased abundance of Fluorides] which results in increased activity of ACHE protein]; Lisinopril inhibits the reaction [Sodium Fluoride results in decreased activity of ACHE protein]; Taurine inhibits the reaction [Sodium Fluoride results in decreased activity of ACHE protein] | PMID:27840156 PMID:31710167 PMID:32627286 PMID:33609566 | |
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