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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735878
Species: Homo sapiens
RGD Object: Gene
Symbol: ACHE
Name: acetylcholinesterase (Yt blood group)
Acc ID: CHEBI:38832
Term: phosphamidon
Definition: An organophosphate nematicide that has formula C10H19ClNO5P.
Chemical ID: MESH:D010707
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ACHEdecreases activityEXP 6480464CTDPhosphamidon results in decreased activity of ACHE proteinPMID:4859365 PMID:8783813
ACHEmultiple interactionsEXP 6480464CTD[Phosphamidon co-treated with Dichlorvos] results in decreased activity of ACHE protein; asoxime chloride inhibits the reaction [Phosphamidon results in decreased activity of ACHE protein]; HLo 7 inhibits the reaction [Phosphamidon results in decreased activity of ACHE protein]; Obidoxime Chloride inhibits the reaction [Phosphamidon results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Phosphamidon results in decreased activity of ACHE protein]PMID:4859365 PMID:8783813
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