GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | ACHE | decreases expression | ISO | Ache (Rattus norvegicus) | 6480464 | CTD | Copper results in decreased expression of ACHE protein | PMID:23613148 | ACHE | increases activity | ISO | Ache (Rattus norvegicus) | 6480464 | CTD | Copper results in increased activity of ACHE protein | PMID:23354609 | ACHE | multiple interactions | ISO | Ache (Rattus norvegicus) | 6480464 | CTD | [Copper Sulfate results in increased abundance of Copper] which results in decreased activity of ACHE protein; Copper inhibits the reaction [Aluminum results in decreased activity of ACHE protein]; Rutin inhibits the reaction [[Copper Sulfate results in increased abundance of Copper] which results in decreased activity of ACHE protein] | PMID:23354609 PMID:32881150 | ACHE | multiple interactions | ISO | Ache (Mus musculus) | 6480464 | CTD | [Copper co-treated with Cholesterol] results in increased activity of ACHE protein; Clioquinol inhibits the reaction [[Copper co-treated with Cholesterol] results in increased activity of ACHE protein] | PMID:25856695 | | ||||||||||||||||||||||
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