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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735878
Species: Homo sapiens
RGD Object: Gene
Symbol: ACHE
Name: acetylcholinesterase (Yt blood group)
Acc ID: CHEBI:2555
Term: aldicarb
Definition: The oxime carbamate resulting from the addition of 2-methyl-2-(methylsulfanyl)propanaldoxime to methyl isocyanate. A member of the class of oxime carbamate insecticides, aldicarb is a mixture of E and Z isomers; it is not known which isomer is more active.
Chemical ID: MESH:D000448
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ACHEdecreases activityEXP 6480464CTDAldicarb results in decreased activity of ACHE proteinPMID:16256972 PMID:21251949 PMID:23962483 PMID:27132127 PMID:33844597 PMID:8134223
ACHEdecreases activityISOAche (Rattus norvegicus)6480464CTDAldicarb results in decreased activity of ACHE proteinPMID:14644616 PMID:21251949
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