GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | ACHE | decreases activity | EXP | | 6480464 | CTD | methylparaoxon results in decreased activity of ACHE protein | PMID:17265452 PMID:18804659 PMID:22982773 PMID:27132127 | ACHE | multiple interactions | EXP | | 6480464 | CTD | 4-(aminocarbonyl)-1-(3-(4-((E)-(hydroxyimino)methyl)pyridinium-1-yl)propyl)pyridinium dibromide inhibits the reaction [methylparaoxon results in decreased activity of ACHE protein]; asoxime chloride inhibits the reaction [methylparaoxon results in decreased activity of ACHE protein]; K-48 compound inhibits the reaction [methylparaoxon results in decreased activity of ACHE protein]; N,N'-monomethylenebis(pyridiniumaldoxime) inhibits the reaction [methylparaoxon results in decreased activity of ACHE protein]; Obidoxime Chloride inhibits the reaction [methylparaoxon results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [methylparaoxon results in decreased activity of ACHE protein] | PMID:17265452 PMID:22982773 | ACHE | decreases activity | ISO | Ache (Rattus norvegicus) | 6480464 | CTD | methylparaoxon results in decreased activity of ACHE protein | PMID:12478623 PMID:18761328 PMID:26965078 PMID:33497710 | ACHE | decreases activity | ISO | Ache (Mus musculus) | 6480464 | CTD | methylparaoxon results in decreased activity of ACHE protein | PMID:33176172 | | ||||||||||||||||||||||
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