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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735868
Species: Homo sapiens
RGD Object: Gene
Symbol: NQO1
Name: NAD(P)H quinone dehydrogenase 1
Acc ID: CHEBI:64243
Term: monosodium L-glutamate
Definition: An optically active form of monosodium glutamate having L-configuration.
Chemical ID: MESH:D012970
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NQO1decreases expressionISONqo1 (Mus musculus)6480464CTDSodium Glutamate results in decreased expression of NQO1 mRNAPMID:29679905
NQO1increases expressionISONqo1 (Mus musculus)6480464CTDSodium Glutamate results in increased expression of NQO1 mRNAPMID:25473020
NQO1multiple interactionsISONqo1 (Mus musculus)6480464CTD[Plant Extracts co-treated with Sodium Glutamate] results in increased activity of NQO1 protein; Sodium Glutamate results in increased expression of and results in increased activity of NQO1 protein; Tea inhibits the reaction [Sodium Glutamate results in decreased expression of NQO1 mRNA]PMID:25473020 PMID:26319613 PMID:29679905
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